Prof. Hu's
Research Group
Xiao Hu, Ph.D
Associate Professor Department of Physics and Astronomy, Rowan University
Office 101J, Science Hall, 201 Mullica Hill Road, Glassboro, NJ 08028-1701 Phone: (856)-256-4860 Email: hu@rowan.edu |
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PROFESSIONAL
EXPERIENCE
Assistant Professor, Department of Physics and Astronomy, Rowan University, NJ (Fall 2012 - Spring 2017) (with Joint Appointments in Department of Biomedical and Translational Sciences, Department of Biomedical Engineering, Rowan University; and a Secondary Appointment in Department of Biomedical Sciences, Cooper Medical School of Rowan University) Research Associate, Department of Biomedical Engineering, Tufts University, MA (Jan-Aug, 2012)
Postdoctoral Fellow, Department of Biomedical Engineering, NIH P41 Tissue Engineering Resource Center (TERC), Tufts Advanced Technology Laboratory, Tufts University, MA (2009 - 2011)
Research Assistant, Department of Physics and Astronomy, Tufts University, MA (2004 - 2009)
Teaching Assistant, Department of Physics and Astronomy, Tufts University, MA (2003 - 2008) Lab Research Assistant, Department of Physics, Nanjing University, China (2002 - 2003)
PublicationS
Full list see Publications
section above Since Fall 2012: 1. Xiao Hu, Min D. Tang-Schomer, Wenwen Huang, Guokui Qin, Xiao-Xia Xia, Anthony S. Weiss, David L. Kaplan. Charge-Tunable Autoclaved Silk-Tropoelastin Protein Alloys That Control Neuron Cell Responses. Advanced Functional Materials (2013), in press (DOI: 10.1002/adfm.201202685). 2. Peggy Cebe, Xiao Hu, David Kaplan, Evgeny Zhuravlev, Andreas Wurm, Daniella Arbeiter, Christoph Schick. Beating the Heat - Fast Scanning Melts Beta Sheet Crystals. (Nature) Scientific Reports, 3, 1130, (2013). 3. Eleanor M Pritchard, Xiao Hu, Violet Finley, Catherine K Kuo, David L Kaplan. Effect of Silk Protein Processing on Drug Delivery from Silk Films. Macromolecular Bioscience (2013), in press (DOI: 10.1002/mabi.201200323). 4. Danyu Yao, Sen Dong, Qiang Lu, Xiao Hu, David L Kaplan, Bingbo Zhang, Hesun Zhu. Salt-Leached Silk Scaffolds with Tunable Mechanical Properties. Biomacromolecules, 13(11), 3723-3729, (2012). 5. Guokui Qin, Patrick B. Dennis, Yuji Zhang, Xiao Hu, Jason E. Bressner, Zhongyuan Sun, Wendy J. Crookes-Goodson, Rajesh R. Naik, Fiorenzo G. Omenetto, David L. Kaplan. Recombinant Reflectin-Based Optical Materials. Journal of Polymer Science: Part B: Polymer Physics 51, 254-264, (2013).
2012: 6. Review: Xiao Hu, Peggy Cebe, Anthony S. Weiss, Fiorenzo Omenetto, David L. Kaplan. Protein-Based Composite Materials. Materials Today, 15(5), 208-215, (2012). 7. Guokui Qin*/ Xiao Hu*, Peggy Cebe, David Kaplan. Mechanism of resilin elasticity. Nature Communications, (2012). (*Equal contribution) 8. Jeney Zhang*, Eleanor Pritchard*, Xiao Hu, Thomas Valentin, Bruce Panilaitis, Fiorenzo G. Omenetto, David L. Kaplan. Stabilization of vaccines and antibiotics in silk and eliminating the cold chain. PNAS (Proceedings of the National Academy of Sciences of the United States of America), 109(30), 11981-11986, (2012). (*Equal contribution) 9. Rangam Rajkhowa, Xiao Hu, Takuya Tsuzuki, David L. Kaplan, Xungai Wang. Structure and Biodegradation Mechanism of Milled Bombyx mori Silk Particles. Biomacromolecules, 13(8), 2503-2512, (2012). 10. Cencen Zhang, Dawei Song, Qiang Lu, Xiao Hu, David L. Kaplan, Hesun Zhu. Flexibility Regeneration of Silk Fibroin in Vitro. Biomacromolecules, 13(7), 2148-2153, (2012). 11. F. Philipp Seib, Manfred F. Maitz, Xiao Hu, Carsten Werner, David L. Kaplan Impact of processing parameters on the haemocompatibility of Bombyx mori silk films. Biomaterials, 33, 1017-1023, (2012). (IF=7.882) 12. Shuo Sun, Ming Wang, Sarah Knupp, Yadira Soto-Feliciano, Xiao Hu, David Kaplan, Robert Langer, Daniel Anderson, Qiaobing Xu. Combinatorial Library of Lipidoids for In Vitro DNA Delivery. Bioconjugate Chemistry, 23(1), 135-140, (2012). 13. A.L. Oliveira, L. Sun, H.J. Kim, Xiao Hu, W. Rice, J. Kluge, R. L. Reis and D. L. Kaplan Aligned Silk-Based 3D Architectures for Contact Guidance in Tissue Engineering. Acta Biomaterialia, 8(4), 1530-1542, (2012). (IF=4.822)
2011: 14. Xiao Hu*, Sang-Hyug Park*, Eun Seok Gil, Xiao-Xia Xia, Anthony S. Weiss, David L. Kaplan. The influence of elasticity and surface roughness on myogenic and osteogenic-differentiation of cells on silk-elastin biomaterials. Biomaterials, 32(34), 8979-89, (2011). (*Equal contribution) 15. Xiao Hu, Karen Shmelev, Lin Sun, Eun-Seok Gil, Sang-Hyug Park, Peggy Cebe, David L. Kaplan. Regulation of Silk Material Structure by Temperature-Controlled Water Vapor Annealing. Biomacromolecules, 12(5), 1686-1696, (2011). 16. Book Chapter: Xiao Hu and David L. Kaplan. Comprehensive Biomaterials: Vol. 2, 2.212 Silk Biomaterials, Editors-Paul Ducheyne, Kevin E Healy, Dietmar E Hutmacher etc.- Elsevier Ltd., Pages 207-219, (2011). (Print ISBN: 9780080553023; Electronic ISBN: 9780080552941). 17. Wenwen Huang, Sreevidhya Krishnaji, Xiao Hu, David Kaplan, Peggy Cebe. Heat Capacity of Spider Silk-like Block Copolymers. Macromolecules, 2011, 44(13), 5295-5305, (2011). 18. Guokui Qin*, Amit Rivkin*, Shaul Lapidot, Xiao Hu, Shira B. Arinos, Or Dgany, Oded Shoseyov, David L. Kaplan. Recombinant Exon-Encoded Resilins for Elastomeric Biomaterials. Biomaterials, 32(35), 9231-9243, (2011). (*Equal contribution) 19. Xiao-Xia Xia, Qiaobing Xu, Xiao Hu, Guokui Qin, and David L. Kaplan. Tunable Self-Assembly of Genetically Engineered Silk-Elastin-Like Protein Polymers. Biomacromolecules, 12(11), 3844-3850, (2011). 20. Michelle Kinahan, Emmanouela Filippidi, Sarah Koster, Xiao Hu, Heather M. Evans, Thomas Pfohl, David L. Kaplan, Joyce Wong. Tunable Silk: Using Microfluidics to Fabricate Silk Fibers with Controllable Properties. Biomacromolecules, 12(5), 1504-1511, (2011). 21. Tara D. Sutherland, Jeffrey S. Church, Xiao Hu, Mickey G. Huson, David L. Kaplan, Sarah Weisman. Single honeybee silk protein mimics properties of multi-protein silk. PLoS ONE, 6(2), e16489, (2011). 22. Lindsay S. Wray, Xiao Hu, Daniel Schmidt, David L. Kaplan. Effect of Processing on Silk-Based Biomaterials: Reproducibility and Biocompatibility. Journal of Biomedical Materials Research-Part B, 99(1), 89-101, (2011).
2010: 23. Xiao Hu, Xiuli Wang, Jelena Rnjak, Anthony S. Weiss, David L. Kaplan. Biomaterials derived from silk-tropoelastin protein systems. Biomaterials, 31(32), 8121-8131, (2010). 24. Xiao Hu, Qiang Lu, Lin Sun, Peggy Cebe, Xiaoqin Wang, Xiaohui Zhang, David Kaplan. Biomaterials from Ultrasonication-Induced Silk Fibroin-Hyaluronic Acid Hydrogels. Biomacromolecules, 11, 3178-3188, (2010). 25. Andreas Lammel, Xiao Hu, Sang-Hyug Park, David L. Kaplan, Thomas Scheibel. Controlling silk fibroin particle features for drug delivery, Biomaterials, 31, 4583-4591, (2010). 26. Corinne R. Wittmer, Xiao Hu, Pierre-Chanel Gauthier, Sarah Weisman, David L. Kaplan, Tara D. Sutherland. Production, structure and in vitro degradation of electrospun honeybee silk nanofibers. Acta Biomaterialia, 7(10), 3789-3795, (2011). 27. Qiang Lu, Xiaoqin Wang, Xiao Hu, Peggy Cebe, Fiorenzo Omenetto, David L. Kaplan. Stabilization and Release of Enzymes from Silk Films, Macromolecular Bioscience, 10, 359-368, (2010). 28. Xiao Hu, Guokui Qin, Peggy Cebe, David Kaplan Structure and Elasticity Mechanism of Full Length Resilin Proteins. Proceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference, 2 pages. 29. Guokui Qin, Shaul Lapidot, Keiji Numata, Xiao Hu, Sigal Meirovitch, Mara Dekel, Itai Podoler, Oded Shoseyov, David Kaplan. Expression, cross-linking and characterization of recombinant chitin binding resilin. Proceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference, 2 pages. 30. Xiao Hu, Guokui Qin, Peggy Cebe, David Kaplan Dynamic Structure Study of Synthetic Resilin Biopolymers. Proceedings of the American Chemical Society, Polym. Mater. Sci. Eng., 2 pages. (2010 Fall Meeting)
2009: 31. Xiao Hu, Qiang Lu, David Kaplan, Peggy Cebe. Microphase Separation Controlled Beta Sheet Crystallization Kinetics in Fibrous Proteins. Macromolecules, 42 (6), 2079-2087, (2009). 32. Xiao Hu, David Kaplan, Peggy Cebe. Thermal Analysis of Protein-Metallic Ion Systems. J. Thermal Analysis, 96, 827-834, (2009). 33. Xiaoqin Wang, Tuna Yucel, Qiang Lu, Xiao Hu, David L. Kaplan, Silk Nanospheres and Microspheres from Silk/PVA Blend Films. Biomaterials, 31, 1025-1035, (2009). 34. Lei Yu, Xiao Hu, David Kaplan, Peggy Cebe. Dielectric Relaxation Spectroscopy of Hydrated and Dehydrated Silk Fibroin Cast from Aqueous Solution. Biomacromolecules, 11(10), 2766-2775, (2010). 35. Shenzhou Lu, Xiaoqin Wang, Qiang Lu, Xiao Hu, Neha Uppal, Fiorenzo Omenetto, David Kaplan. Stabilization of Enzymes in Silk Films, Biomacromolecules, 10(5), 1032-1042, (2009). 36. Guokui Qin, Shaul Lapidot, Keiji Numata, Xiao Hu, Sigal Meirovitch, Mara Dekel, Itai Podoler, Oded Shoseyov, David Kaplan. Expression, cross-linking and characterization of recombinant chitin binding resilin. Biomacromolecules, 10, 3227-3234, (2009). (IF=5.325) 37. Qiang Lu, Xiao Hu, Xiaoqin Wang, Jonathan Klugea, Shenzhou Lu, Peggy Cebe, David L. Kaplan. Water-Insoluble Silk Films with Silk I Structure. Acta Biomaterialia, 6, 1380-1387, (2009). 38. Qiang Lu, Xiaohui Zhang, Xiao Hu, David L Kaplan. Green Process to Prepare Silk Fibroin/Gelatin Biomaterial Scaffolds. Macromolecular Bioscience, 10, 289-298, (2009). 39. Antonella Motta, Devid Maniglio, Claudio Migliaresi, Hyeon-Joo Kim, Xianyan Wang, Xiao Hu, David Kaplan, Silk Fibroin Processing and Thrombogenic Responses, J. Biomaterials Science, Polymer Edition, 20 (13), 1875-1897, (2009). 40. Xiao Hu, Qiang Lu, David Kaplan, Peggy Cebe. Microphase separation restricted beta sheet self-assembly and crystallization kinetics in silk fibroin protein. Proceedings of the American Chemical Society Polym. Mater. Sci. Eng., 101, 1278-1279, (2009). 41. A. Wurm, D. Arbeiter, Xiao Hu, D. Kaplan, P. Cebe, and C. Schick. Crystallization and melting of fibrous silk protein by fast calorimetric methods. Proceedings of the 37th North American Thermal Analysis Society (NATAS) annual conference, Fall 2009.
2008: 42. Xiao Hu, David Kaplan, Peggy Cebe. Dynamic Protein-Water Relationships during Beta Sheet Formation. Macromolecules, 41(11), 3939-3948, (2008). 43. M. Pyda, Xiao Hu, Peggy Cebe. Heat Capacity of Silk Fibroin Based on the Vibration-Motion of Poly(amino acid)s in the Absence and in the Presence of Water. Macromolecules, 41(13), 4786-4793, (2008). 44. Huipeng Chen, Xiao Hu, and Peggy Cebe. Thermal Properties and Phase Transitions in Nylon-6 and Silk Fibroin Blends. J. Thermal Analysis, 93(1), 201-206, (2008). 45. Featured article: Xiao Hu, David Kaplan, Peggy Cebe. Thermal Analysis of Protein-Metallic Ion Systems. NATAS Notes, 40(4), 9-18, Fall 2008 (North American Thermal Analysis Society, www.natasinfo.org). 46. Featured article: M. Pyda, Xiao Hu, Peggy Cebe. Heat Capacity of Silk Fibroin Based on the Vibrational-Motion of Poly(amino acid)s. NATAS Notes, 40(4), 20-27, Fall 2008 (North American Thermal Analysis Society, www.natasinfo.org).
2007: 47. Xiao Hu, David Kaplan, Peggy Cebe. Effect of Water on Thermal Properties of Silk Fibroin. Thermochimica Acta, 461(1-2), 137-144, (2007). 48. Xiaoqin Wang, Esther Wenk, Xiao Hu, Guillermo R. Castro, Lorenz Meinel, Xianyan Wang, Chunmei Li, Hans Merkle, David Kaplan; Silk coatings on PLGA and alginate microspheres for protein delivery, Biomaterials, 28, 4161-4169, (2007). 49. Xianyan Wang, Xiao Hu, Andrea Daley, Olena Rabotyagova, Peggy Cebe, and David Kaplan. Nanolayer biomaterial coatings of silk fibroin for controlled release. Journal of Controlled Release, 121, 190-199, (2007). 50. Xiao Hu, David Kaplan, Peggy Cebe. The Role of Water Molecules in the Thermal Crystallization of Silk Fibroin Protein Proceedings of the American Chemical Society Polym. Mater. Sci. Eng., 97, 559-560, (2007). 51. Xiao Hu, David Kaplan, Peggy Cebe. Beta Pleated Sheet Crystals in Silk Fibroin Proceedings of the American Chemical Society Polym. Mater. Sci. Eng., 97, 178-179, (2007). 52. Xiao Hu, David Kaplan, Peggy Cebe. Thermal Crystallization of Silk Fibroin Protein Proceedings of the 35th North American Thermal Analysis Society (NATAS) annual conference, Fall 2007.
2006: 53. Xiao Hu, David Kaplan, Peggy Cebe. Determining Beta Sheet Crystallinity in Fibrous Proteins by Thermal Analysis and Infrared Spectroscopy. Macromolecules, 39, 6161-6170 (2006). (IF=4.837) (Citation > 110)
2005: 54. Xiao Hu, Peggy Cebe. Isothermal Crystallization Kinetics Study of Regenerated Bombyx mori Silk Fibroin Film Proceedings of the American Chemical Society Polym. Mater. Sci. Eng., 93, 652-653, (2005). Invited
talks and visits
New list since 2013 see News section above 1. (Invited talk and visit) Department of Physics and Astronomy, Rowan University, February 20-21th, 2011. 2. (Invited talk and visit) Department of Physics, Worcester Polytechnic Institute (WPI), February 27th- March 1st, 2011. 3. (Invited talk and visit) Department of Physics, University of Massachusetts Boston, March 15th, 2011. 4. (Invited talk and visit) Department of Physics, Nanjing University, Nanjing, China, June 6th, 2011. 5. (Invited talk and visit) China National Engineering Laboratory for Modern Silk, Soochow University, Suzhou, China, June 16-17th, 2011. 6. (Visiting scholar and invited talk) School of Molecular Bioscience, The University of Sydney, Sydney, Australia, November 09-19th, 2011. 7. (Invited visit) Australian Commonwealth Scientific and Research Organization (CSIRO) Ecosystem Sciences/Australian National University, Canberra, Australia, November 20-22th, 2011. 8. (Invited talk and visit) Centre for Material and Fibre Innovation (CMFI), Deakin University, Geelong, Australia, November 23-26th, 2011. 9. (Invited talk and visit) Department of Physics and Astronomy, Rowan University, January 29-30th, 2012. 10. (Invited talk and visit) Department of Physics and Astronomy, Clemson University, February 08-10th, 2012. 11. (Invited speaker) Silk-Tropoelastin Biomaterial Alloys, Keystone Symposia Conference (Regenerative Tissue Engineering and Transplantation), Breckenridge, Colorado, April 01-06th, 2012. 12. (Keynote speaker) Fibrous Protein Alloys for New Biomaterials, The 9th World Biomaterials Congress, Symposium 37.3, Chengdu, China, June 1st-5th, 2012. 13. (Invited speaker) Protein-based Biomaterials: Self-assembly and Medical Applications. Biopolymers, Bio-based Polymers Session, ACS Northeast Regional Meeting, Rochester, NY, Oct. 2012. 14. (Invited speaker) BME Seminar, New Jersey Institute of Technology, October 2012. 15. (Invited talk and visit) Department of Materials Science & Engineering, Drexel University, December 2012.
International
Conference PresentationS (First author ONLY) New list since 2013 see News section above Oral Presentations 1. Precursor to Beta-Sheet Crystal Formation in the Polymer-Water System. Xiao Hu, David Kaplan and Peggy Cebe; Material Research Society Conference (MRS), Boston, Nov. 2007. 2. Beta-sheet Crystallization in Silk Fibroin Film. Xiao Hu, David Kaplan, Peggy Cebe; American Chemical Society Conference (ACS), Boston, Aug. 2007. 3. Determining Beta Sheet Crystallinity in Fibrous Proteins by Thermal Analysis and Infrared Spectroscopy. Xiao Hu, David Kaplan , Peggy Cebe; American Physical Society Conference, Denver (APS), Mar. 2007. 4. Silk-Tropoelastin Biomaterial Alloys. Xiao Hu, Wenwen Huang, Anthony S. Weiss, David L. Kaplan; 40th North American Thermal Analysis Society Conference, Orlando, Aug. 2012. 5. Dynamic Elasticity Model of Resilin Proteins. Xiao Hu, Solomon Duki. American Physical Society March Meeting, Baltimore, Maryland, March 18-22th, 2013. (abstract)
Poster Presentations 1. Ultrasound induced Silk-Hyaluronic Acid Blend Hydrogel. Xiao Hu, Qiang Lu, Peggy Cebe, Xiaoqin Wang, Xiaohui Zhang, David Kaplan; Biomedical Engineering Society (BMES) Meeting, Pittsburgh, Oct., 2009. 2. Impact of Metallic Ions on Beta Sheet Crystallization of Silk Fibroin Proteins Xiao Hu, Qiang Lu, Wenwen Huang, David Kaplan, and Peggy Cebe; North American Thermal Analysis Society Conference, Lubbock, TX, Aug. 2009. 3. Crystallization Kinetics and Self-assembly of Beta Sheet Crystals in Silk Multiblock Proteins. Xiao Hu, Qiang Lu, David Kaplan, and Peggy Cebe; North American Thermal Analysis Society Conference, Lubbock, TX, Aug. 2009. 4. Microphase separation restricted beta sheet self-assembly and crystallization kinetics in silk fibroin protein. Xiao Hu, Qiang Lu, David Kaplan, Peggy Cebe; American Chemical Society Conference, Washington D.C., Aug. 2009. 5. Impact of Protein-Metal Ion Interactions on the Crystallization of Silk Fibroin Protein. Xiao Hu, Qiang Lu, David Kaplan, Peggy Cebe; American Physical Society Conference, Pittsburgh, Mar. 2009. 6. Microphase Separation Controlled Beta Sheet Crystallization Kinetics in Silk Fibroin Protein. Xiao Hu, Qiang Lu, David Kaplan, Peggy Cebe; American Physical Society Conference, Pittsburgh, Mar. 2009. 7. Self-assembly Kinetics of Beta Pleated Sheets in Fibrous Protein. Xiao Hu, Qiang Lu, David Kaplan and Peggy Cebe; Material Research Society Conference, Boston, Dec.2008. 8. Dynamic Protein-Water Relationships During Beta Sheet Formation. Xiao Hu, David Kaplan, Peggy Cebe; North American Thermal Analysis Society Conference, Atlanta, Aug. 2008. (Winner of Springer Best Poster Award 2008 in the conference) 9. Role of Water Molecules in the Thermal Crystallization of Silk Fibroin Protein. Xiao Hu, David Kaplan, Peggy Cebe; American Chemical Society Conference, Boston, Aug. 2007 10. Mechanism of Thermal Crystallization in Silk Fibroin. Xiao Hu, David Kaplan , Peggy Cebe; American Physical Society Conference, Denver, Mar. 2007. 11. Determining Beta Sheet Crystallinity in Silks Films. Xiao Hu, David Kaplan and Peggy Cebe. Material Research Society Conference, Boston, Nov.2006. (Honored as MRS Best Poster Nominee 2006 in the conference) 12. Isothermal Crystallization Kinetics Study of Regenerated Bombyx Mori Silk Fibroin Film. Xiao Hu and Peggy Cebe; American Chemical Society Conference, Washington D.C., Aug. 2005. 13. Structure and Elasticity Mechanism of Full Length Resilin Proteins. Xiao Hu, Guokui Qin, Peggy Cebe, David Kaplan. IEEE 36th Annual Northeast Bioengineering Conference, March 2010. 14. Dynamic Structure Study of Synthetic Resilin Biopolymers. Xiao Hu, Guokui Qin, Peggy Cebe, David Kaplan; American Chemical Society Conference (ACS), Boston, Aug. 2010. 15. Silk-Human Tropoelastin Blend Biomaterials. Xiao Hu, Xiuli Wang, Jelena Rnjak, Anthony S. Weiss, David L. Kaplan; Biomedical Engineering Society (BMES) Meeting, Austin, Oct., 2010. 16*. Impact of the Hydrophilic Block on the Glass Transition of Spider Silk Block Copolymers. Wenwen Huang, Krishnaji Sreevidhya, Xiao Hu, David Kaplan, Peggy Cebe; North American Thermal Analysis Society Conference, Philadelphia, Aug. 2010. (Winner of Springer Best Poster Award 2010 in the conference) 17. Dynamic Mechanism of Resilin Elasticity. Xiao Hu, Guokui Qin, Peggy Cebe, David Kaplan; 40th North American Thermal Analysis Society Conference, Orlando, Aug. 2012.
Manuscript
Reviewer activities
1. Reviewer for the journal Macromolecules, from 02/2010 2. Reviewer for the journal Biomacromolecules, from 05/2009 3. Reviewer for the journal The Journal of Physical Chemistry, from 04/2010 4. Reviewer for the journal Polymer, from 05/2010 5. Reviewer for the journal Polymer International, from 08/2009 6. Reviewer for the journal Thermochimica Acta, from 11/2009 7. Reviewer for the journal Acta Biomaterialia, from 04/2010 8. Reviewer for the journal Journal of Thermal Analysis and Calorimetry, from 09/2010 9. Reviewer for the journal Macromolecular Materials and Engineering, from 02/2011 10. Reviewer for the journal Journal of Biomaterials Science: Polymer Edition, from 09/2011 11. Reviewer for the journal Applied Physics Letters, from 09/2012 12. Reviewer for the journal Nature Communications, from 04/2013 |