Subash C. Jonnalagadda

Associate Professor

Department of Chemistry and Biochemistry

Rowan University

201 Mullica Hill Road

Glassboro, NJ 08028

e-Mail: jonnalagadda@rowan.edu

Phone: (856) 256-5452

Fax: (856) 256-4478

 

 

Education

 

2005

Ph.D. (Chemistry)

Purdue University, West Lafayette, IN

2000

M.Sc. (Chemistry)

University of Hyderabad, Hyderabad, India

1998

B.Sc. (Chemistry)

Pondicherry University, Pondicherry, India

 

 

Professional Experience

 

2013-present

Associate Professor, Rowan University, Glassboro, NJ

2008-2013

Assistant Professor, Rowan University, Glassboro, NJ

2009-2011

Visiting Assistant Professor (Summer), University of Minnesota, Duluth, MN

2006-2008

Postdoctoral Research Associate, University of Minnesota, Duluth, MN

2005-2006

Postdoctoral Research Associate, University of Pennsylvania, Philadelphia, PA

2000-2005

Graduate Research & Teaching Assistant, Purdue University, West Lafayette, IN

 

 

Current Projects

 

Development of Novel Synthetic Methodologies and Reagents for Organic Synthesis.

Synthesis and Evaluation of Novel Small Molecules as Cancer Chemotherapeutics.

 

 

 

Awards/Fellowships

 

Rowan University Wall of Fame (Teaching), 2013

Eli Lilly Co. International Graduate Scholar, Purdue University, IN, 2000-2005

V.V. Sarma Memorial Gold Medal for Academic Excellence, University of Hyderabad, India, 2000

Visiting Student Research Fellowship - Tata Institute of Fundamental Research, India, 1999

 

 

Publications (undergraduate students underlined)

 

 

1.     Tekkam S.; Alam, M. A.; Just, M. J.; Johnson J. L.; Jonnalagadda S. C.; Mereddy V. R., “Stereoselective Synthesis of Pyroglutamate Natural Product Analogs from α-Aminoacids and their Anti-Cancer EvaluationAnti-Cancer Agents in Medicinal Chemistry 2013, 00, 0000 (Bentham Science Publishers).

2.     Tekkam S.; Johnson J. L.; Jonnalagadda S. C.; Mereddy V. R., “An efficient synthesis of [2.2.1] heterobicyclic pyroglutamatesJ. Het. Chem. 2013, 50, 969-972.

3.     Tekkam S.; Johnson J. L.; Jonnalagadda S. C.; Mereddy V. R., “Concise Synthesis of α-Methylene-β-hydroxy-γ-carboxy-γ-lactams” J. Het. Chem. 2013, 50, 955-958.

4.     Kumar, J. S.; Alam, M. A.; Gurrapu, S.; Nelson, G.; Williams, M.; Corsello, M. A.; Johnson, J. L.; Jonnalagadda, S. C.; Mereddy, V. R.Synthesis and Biological Evaluation of Novel Benzoxaboroles as Potential anti-Microbial and anti-Cancer AgentsJ. Het. Chem. 2013, 50, 814-820.

5.     Gurrapu, S.; Walsh, W. J.; Brooks, J. M.; Jonnalagadda, S. C.; Mereddy, V. R. “Synthesis of Lupane Triterpenoid DerivativesNatural Products, Ind. J. 2012, 8, 115-120.

6.     Tekkam, S.; Alam, M. A.; Jonnalagadda, S. C.; Mereddy, V. R. “Novel methodologies for the synthesis of functionalized pyroglutamates.Chem. Commun. 2011, 47, 3219-3221.

7.     Just, M. J.; Tekkam, S.; Alam, M. A.; Jonnalagadda, S. C.; Johnson, J. L.; Mereddy, V. R. “Stereoselective Synthesis of Functionalized PyroglutamatesTetrahedron Lett.  2011, 52, 5349-5351.

8.     Jonnalagadda, S. C.; Verga, S. R.; Patel, P. D.; Reddy, A. V.; Srinivas, T.; Scott, P. M.; Mereddy, V. R. “Novel methodologies for the synthesis of functionalized lipophilic carboranes.Applied Organometallic Chemistry, 2010, 24, 294-300.

9.     Kumar, J. S.; Bashian, C. M.; Corsello, M. A.; Jonnalagadda, S. C.; Mereddy, V. R. “Development of practical methodologies for the synthesis of functionalized benzoboroxoles.Tetrahedron Lett.  2010, 51, 4482-4485.

10.  Kumar, J. S.; Jonnalagadda, S. C.; Mereddy, V. R. “An efficient boric acid-mediated preparation of α-hydroxyamides.Tetrahedron Lett.  2010, 51, 779-782.

11.  Jonnalagadda, S. C.; Cruz, J.; Connell, R. J.; Scott, P.; Mereddy, V. R. “Synthesis of α-carboranyl-α-acyloxy-amides as potential BNCT agents.Tetrahedron Lett.  2009, 50, 4314-4317.

12.  Gopala, J.; Jonnalagadda, S. C.; Mereddy, V. R. “A concise synthesis of γ-carboxy-γ-lactones.  Org. Chem. Ind. J. 2008, 4, 513-517.

13.  Jonnalagadda, S. C.; Just, M. J.; Wiseman, A. C.; Mereddy, V. R. Soft drinks catalyzed hydrolysis and alcoholysis of epoxides.”   Org. Chem. Ind. J. 2008, 4, 314-316.

14.  Reddy, A. V.; Gopalakrishna, J.; Kovich, K. T.; Jonnalagadda, S. C.; Mereddy, V. R. A convenient methodology for the synthesis of functionalized nitrogen mustards Org. Chem. Ind. J. 2008, 4, 309-313.

15.  Reddy, V. J.; Jonnalagadda, S. C.; Reddy, M. V. R. “Concise Syntheses of w-Borono-a-Amino AcidsOrg. Biomol. Chem. 2007, 5, 889-891.

16.  Gunasekera, D. S.; Gerold, D. A.; Aalderks, N. A.; Jonnalagadda, S. C.; Kiprof, P.; Zhdankin, V. V.; Reddy, M. V. R. “Practical synthesis and applications of benzoboroxolesTetrahedron 2007, 63, 9401-9405.

17.  Ramachandran, P. V.; Jonnalagadda, S. C.; Prabhudas, B.; Pratihar, D.; Mereddy, V. R.Studies towards the synthesis of EpothiloneOrg. Biomol. Chem. 2005, 3, 3812-3824.

18.  Ramachandran, P. V.; Prabhudas, B.; Jonnalagadda, S. C.; Mereddy, V. R.Diastereoselective dihydroxylation and regioselective deoxygenation of dihydropyranones: “Application towards the synthesis of two subunits of (+)-DiscodermolideJ. Org. Chem. 2004, 69, 6294-6303.

19.  Ramachandran, P. V.; Prabhudas, B.; Jonnalagadda, S. C.; Reddy, M. V. R.; Brown, H. C. “Preparative-scale synthesis of both antipodes of B-γ-dimethylallyldiisopinocampheylborane: Application for the synthesis of a subunit of epothiloneTetrahedron Lett.  2004, 45, 1011-1013.

20.  Ramachandran, P. V.; Prabhudas, B.; Pratihar, D.; Jonnalagadda, S. C.; and Reddy, M. V. R. “Stereoselective synthesis of the C7-C21 segment of epothilone A via asymmetric alkoxyallyl- and crotylborationTetrahedron Lett. 2003, 44, 3745-3748.

21.  Ramachandran, P. V.; Jonnalagadda, S. C.; and Reddy, M. V. R. “Stereoselective syntheses of (+)-goniodiol, (-)-8-epigoniodiol, and (+)-9-deoxygoniopypyrone via alkoxyallylboration and ring-closing metathesisJ. Org. Chem. 2002, 67, 7547-7550.

 

Book Chapters/Review Articles

 

1.     Jonnalagadda, S. C.; Corsello, M. A.; Sleet, C. E. Betulin-Betulinic Acid Natural Product Based Analogs as Anti-Cancer Agents”, Anti-Cancer Agents in Medicinal Chemistry 2013, 00, 0000 (Bentham Science Publishers).

2.     Jonnalagadda, S. C.; Corsello, M. A.; Hetzell, B. R.; Mereddy, V. R. “Synthetic Applications of Suzuki-Miyaura Cross Coupling Reaction  pp 741-805,  inBoron Science: New Technologies & Applications” Ed. Hosmane, N. R. CRC Press. 2012.

3.     Jonnalagadda, S. C.; Kumar, J. S.; Cirri, A.; Mereddy, V. R. “Asymmetric Allylation of Carbonyl Compounds via Organoboranes  pp 639-674,  in “Boron Science: New Technologies & Applications” Ed. Hosmane, N. R. CRC Press. 2012.

4.     Jonnalagadda, S. C.; Mereddy, V. R. “(B)-(E)-γ-Alkoxyallyldiisopinocampheylboranee-Encyclopedia of Reagents for Organic Synthesis (e-EROS) Article Online Posting Date: September 15, 2009.

5.     Jonnalagadda, S. C.; Mereddy, V. R. “(B)-(Z)-γ-Methoxyallyldiisopinocampheylboranee-Encyclopedia of Reagents for Organic Synthesis (e-EROS) Article Online Posting Date: March 15, 2009.

6.     Jonnalagadda, S. C.; Reddy, V. J.; Reddy, M. V. R. “Five-membered Heterocycles With 3 Or 4 Heteroatoms Including At Least One Boron Atom" in Comprehensive Heterocyclic Chemistry III (Elsevier) 2008, 615-654.

7.     Jonnalagadda, S. C.; Mereddy, V. R.Allylboration using (B)-γ-Alkoxyallyldiisopinocampheyl-boranes: Highly Stereoselective Reactions for Organic SynthesisARKIVOC, 2007, 121-145.

8.     Ramachandran, P. V.; Jonnalagadda, S. C.Pinacolboranee-Encyclopedia of Reagents for Organic Synthesis (e-EROS) Article Online Posting Date: October 15, 2005.

9.     Ramachandran, P. V.; Jonnalagadda, S. C.Catecholboranee-Encyclopedia of Reagents for Organic Synthesis (e-EROS) Article Online Posting Date: October 15, 2005.

10.  Ramachandran, P. V.; Jonnalagadda, S. C.Dichloroborane-Methylsulfidee-Encyclopedia of Reagents for Organic Synthesis (e-EROS) Article Online Posting Date: October 15, 2005.

 

 

Courses Taught at Rowan University

 

Fall 2013

Organic Chemistry I (CHEM-07200, CRN 40479)

Fall 2013

Pharmaceutical Chemistry (CHEM-07492, CRN 43957)

Fall 2013

Seminar (CHEM-05450, CRN 40465)

Spring 2013

Organic Spectroscopic Analysis (CHEM-07470, CRN 23223)

Spring 2013

Organic Chemistry II (CHEM-07201, CRN 21640)

Fall 2012

Organic Chemistry I (CHEM-07200, CRN 40507 & 40508)

Fall 2012

Advanced Organic Chemistry (CHEM-07464, CRN 42796)

Fall 2012

Seminar (CHEM-05450, CRN 40493)

Summer 2012

Organic Preparations (CHEM-07467, CRN 30739)

Spring 2012

Organic Chemistry II (CHEM-07201, CRN 22180 & 22181)

Fall 2011

Organometallic Chemistry (CHEM-05430, CRN 42935 & 42936)

Fall 2011

Organic Chemistry I (CHEM-07200, CRN 41566 & 41603)

Fall 2011

Seminar (CHEM-05450, CRN 40585)

Summer 2011

Organic Chemistry II Lab (CHEM-07201, CRN 30740)

Spring 2011

Organic Chemistry II (CHEM-07201, CRN 23011 & 22415)

Fall 2010

Preparation for College Chemistry (CHEM-05100, CRN 42115)

Fall 2010

Organic Chemistry I  (CHEM-07200, CRN 41263)

Fall 2010

Advanced Organic Chemistry (CHEM-07464, CRN 42919)

Fall 2010

Seminar (CHEM-05450, CRN 40637)

Spring 2010

Organic Chemistry II (CHEM-07201, CRN 20171, 20172, & 23172)

Fall 2009

Organic Chemistry I (CHEM-07200, CRN 40718 & 41915)

Spring 2009

Organic Chemistry II (CHEM-07201, CRN 20195, 20196, & 21560)

Fall 2008

Organic Chemistry I (CHEM-07200, CRN 40846 & 42362)

 

 

Current Research Students

 

Michael Bacani

Senior, BS Biochemistry

Steven Fishbein

Senior, BS Biochemistry

Pallavi Chary

Junior, BS Biochemistry

Melvin Adams

Senior, BS Chemistry

Frank Feraco

Senior, BS Biology

Preston Jones

Senior, BS Biochemistry

Crystal Holt

Junior, BS Biochemistry

 

 

Alumni

 

Steven Verga

BS Biochemistry, 2011

Drexel University School of Medicine (M.D. Program)

Parth Patel

BS Biochemistry, 2012

Rowan (UMDNJ)-SOM (Graduate Program)

Jonathan Cruz

 

 

Valerie Giannone

BS Biochemistry, 2010

Thomas Jefferson University (Pharm.D. Program)

Nora Schmidt

BS Biochemistry, 2010

Thomas Jefferson University (Graduate Program)

Drew Morgan

 

Teacher (Lindenwold High School, NJ)

Christopher Bashian

BS Biology, 2011

Rowan (UMDNJ)-SOM (DO Program)

William Walsh

BS Biology, 2012

South University (PharmD Program)

James Brooks

BS Biology, 2011

 

Joseph Schafer

BS Chemistry, 2011

Teacher (Toms River High School South, NJ)

Anthony Cirri

BS Chemistry, 2011

Penn State University (PhD Program)

Michael Corsello

BS Biochemistry, 2012

University of California Los Angeles (PhD Program)

Samantha Tsang

BS Chemistry, 2011

Benjamin Moore Paints

Brandon Hetzell

BS Biochemistry, 2011

Lake Erie College of Medicine (Pharm.D, Program)

Marc Moses

BS Biochemistry, 2013

 

Kathleen Twomey

BS Chemistry, 2013

University of Maryland Baltimore County (MD Program)

Gabriella Contino

High School Student

Muhlenberg College (BS )

Mujtaba Moosavi

BS Biology, 2012

Temple University (DMD Program)

Marc Illiucci

BS Chemistry, 2011

University of Southern California (PhD Program)

Harison Latimer

BS Physics, 2013

 

Rudy Baskette

BA Chemistry, 2011

Agilent Technologies

Justin Coe

BS Biochemistry, 2012

 

Christopher Sleet

BS Chemistry, 2013

University of Texas Southwestern Medical Center (PhD Program)

Bryan Penczuk

BS Biochemistry, 2013

Temple University (DMD Program)

Eric Barbalace

High School Student

 

Nguyet Do

BS Chemistry, 2012

DuPont

Dennis Carrow

BS Biochemistry,

 

Collin Dube

BS Biochemistry, 2012

DPT Laboratories

Viquar Moosavi

BS Biology, 2013

 

Bella Wight

BS Chemistry, 2013

The College of New Jersey (Graduate Program)

Lucas Solano

BS Chemistry, 2013

University of Minnesota (Graduate Program)

Gregory Carrocino

BS Biochemistry, 2013

DuPont

Jason Smith

BS Biology, 2012

Teacher (Millville Memorial High School)

James Graber

High School Student

Lehigh University (BS)

Fredrick Adams

BS Biochemistry, 2013

 

Kori Vaughn

BS Biology, 2013

 

Mariah Pong

High School Student

 

Siddharth Oruganti

High School Student