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Current
Projects For the past few years, our group has been focusing on two main
areas of research including medicinal chemistry and development of value
added materials from renewable biomass. Medicinal
Chemistry: We have been working on the design and synthesis of novel aza- and boraheterocyclic
compounds as well as betulin-based natural product derivatives for potential
applications as therapeutic agents.
In collaboration with Rowan School of Osteopathic Medicine, we have also
identified few Withaferin-serotonin conjugates as
potential therapeutic options for the treatment of AlzheimersÕ
Disease. Project
1: Development of Novel Methodologies for the Preparation of
Functionalized Benzoboroxoles.
Tetrahedron, 2016,
72, 3795-3801 J. Organomet.
Chem. 2015, 798, 125-131 J. Het. Chem. 2013, 50, 814-820 Tetrahedron Lett. 2010,
51, 4482-4485 Tetrahedron Lett. 2010,
51, 779-782 Project 2: Development
of Betulin-Based Natural Product Derivatives as Cancer Chemotherapeutics.
Anti-Cancer Agents in Med. Chem. 2013, 13,
1477-1499 Natural Products, 2012, 8, 115-120 Value Added Materials from
Renewable Biomass:
Recent efforts in this area have included the
development of new protocols for the effective conversion of biomass derived
cellulosic materials into chemicals such as hydroxymethyl
furfural and furan dicarboxylic acid for
applications as bio-based polymers.
We have also been working on the synthesis of lignin derived polymeric
materials utilizing Baylis-Hillman reaction.
Catalysis Commun. 2015, 58, 179-182 Appl. Catalysis A. 2015,
489, 72-76 |
