Prof. Hu's Research
Group
Publications
Since Fall 2012:
83.Fang Wang, SS Jyothirmayee Aravind, Hao Wu, Joseph Forys, Venkat Venkataraman,
Kandalam Ramanujachary, Xiao Hu*. Tunable green graphene-silk biomaterials:
Mechanism of protein-based nanocomposites. Materials
Science and Engineering: C, (2017), 79, 728-739.
82.Kelsey DeFrates, Theodore Markiewicz, Kayla Callaway, Ye Xue,
John Stanton, David Salas-de la Cruz, Xiao
Hu*. Structure-property relationships
of Thai silk-microcrystalline cellulose biocomposite
materials fabricated from ionic liquid. International Journal of
Biological Macromolecules, 104, 919-928.
81.John Stanton, Ye Xue, Joshua C Waters,
Ashley Lewis, Darrel Cowan, Xiao Hu,
David Salas-de la Cruz. Structure-property
relationships of blended polysaccharide and protein biomaterials in ionic
liquid. Cellulose (2017), 24 (4), 1775-1789.
80.Dave Jao, Ye Xue,
Jethro Medina, Xiao Hu*. Protein-Based Drug-Delivery Materials. Materials
(2017), 10 (5), 517.
79.Raghid Najjar, Yi Luo, Dave
Jao, David Brennan, Ye Xue,
Vince Beachley, Xiao
Hu, Wei Xue. Biocompatible
Silk/Polymer Energy Harvesters Using Stretched PVDF-HFP Nanofibers.
Polymers
(under review).
78.John
Stanton, Ye Xue, Prabhdeep Pandher, Laura Malek, Tyler
Brown, Xiao Hu, David Salas-de la
Cruz. Impact of Ionic Liquid Type on the
Structure, Morphology and Properties of Silk-Cellulose Biocomposite
Materials. International Journal of Biological Macromolecules (under
review).
77.Wei Xue, Xiao Hu, Jeffrey Hettinger. Electronic
Skin Patch For Health Monitoring. US Patent 20170086684, (2017).
76.Maria Torculas, Jethro Medina, Wei Xue,
Xiao Hu*. Protein Based Bioelectronics. ACS
Biomaterials Science & Engineering, (2016), 2
(8), 1211-1223.
75.Phuong-Trang Vu, Ye Xue, Trinh Vuong, Matthew Erbe, Christopher Bennet, Ben Palazzo, Lucas Popielski,
Nelson Rodriguez, Xiao Hu*. Comparative Study of Ultrasonication
Induced and Naturally Self-assembled Silk Fibroin-Wool Keratin Hydrogel
Biomaterials. International Journal of Molecular Science,
(2016), 17(9), 1497.
74.Ye Xue,
Dave Jao, Wenbing Hu, Xiao Hu*. Silk-Silk Blend Materials: A Comparative Study of Mori-Tussah,
Mori-Muga, Mori-Eri, and
Mori-Thai Silk Films. Journal
of Thermal Analysis and Calorimetry, (2016) (DOI 10.1007/s10973-016-5699-9)
73.Dave Jao, Xiaoyang Mou,
Xiao Hu*. Tissue Regeneration: A Silk Road. Journal of Functional Biomaterials. (2016), 7(3), 22.
72.Emanuela Callone, Sandra Dirè, Xiao Hu, Antonella
Motta. Processing Influence on Molecular
Assembling and Structural Conformations in Silk Fibroin: Elucidation by
Solid-State NMR. ACS Biomaterials Science & Engineering,
2 (5), 758-767, (2016).
71.Fang Wang, Phillip
Chandler, Robert Oszust, Eric Sowell, Zachary Graham,
William Ardito, Xiao
Hu*. Thermal and Structural Analysis
of Silk-Polyvinyl Acetate Blends. Journal of Thermal Analysis and Calorimetry, (2016).
70.David A. Brennan, Dave Jao, Michael C. Siracusa, Andrew
R. Wilkinson, Xiao Hu, Vince Z. Beachley. Concurrent
collection and post-drawing of individual electrospun
polymer nanofibers to enhance macromolecular
alignment and mechanical properties. Polymer, (2016), 103(26), 243-250. doi: 10.1016/j.polymer.2016.09.061.
69.Zvi
Shtein, Sigal Meirovitch, Tal Ben-shalom, Shaul
Lapidot, Carmen Tamburu, Xiao
Hu, Jonathan A. Kluge, Uri Raviv, David L.
Kaplan, Oded Shoseyov.
Spider silk-CBD-nanocrystalline cellulose
composites: Mechanism of Assembly. International Journal of Molecular Science,
(2016), 17(9), 1573; doi:10.3390/ijms17091573.
68.(Book Chapter) Ye Xue, Wenbing Hu, Xiao Hu*.
Thermal analysis of natural fibers. In the book: Thermal analysis of textiles and fibers (Woodhead
Publishing Series In Textiles), Elsevier Ltd., (2016), in press and the
full book will be published in 2017.
67.(Peer-Reviewed
Conference Paper) Joseph R. Nalbach,
Dave Jao, Douglas G. Petro, Kyle M. Raudenbush, Shibbir Ahmad, Ye Xue, Xiao Hu,
and Wei Xue, "Fabrication of tunable silk
materials through microfluidic mixers", Proceedings of the ASME 2016
International Mechanical Engineering Congress & Exposition,
publication #: IMECE2016-65623, 2016.
66.(Peer-Reviewed
Conference Paper) Raghid Najjar, Yi Luo, Xiao
Hu, Vince Beachley, and Wei Xue,
"Study of energy harvesting performance of wet-stretched PVDF nanofibers", Proceedings of the ASME 2016 International
Mechanical Engineering Congress & Exposition,
publication #: IMECE2016-66642, 2016.
65.Fang Wang, Nathan Wolf,
Eva-Marie Rocks, Trinh Vuong, Xiao Hu*. Comparative studies of regenerated water-based Mori,
Thai, Eri, Muga and Tussah
silk fibroin films. Journal of Thermal Analysis and Calorimetry, (2015), 122, 1069-1076.
64.Shen-Jun Sheng, Fang
Wang, Qing-Yu Ma, Xiao Hu. Impact of Foaming Air on Melting and
Crystallization Behaviors of Microporous PLA
Scaffolds. Journal of Thermal Analysis and Calorimetry,
(2015), 122, 1077-1088.
63.Shen-Jun Sheng, Xiao Hu, Fang Wang, Qing-Yu Ma, Min-Fen
Gu. Mechanical
and thermal property characterization of poly-L-lactide
(PLLA) scaffold developed using pressure-controllable green foaming technology.
Materials
Science and Engineering C, 49, 612-622, (2015).
62.Xiao Hu,
Solomon Duki, Joseph Forys,
Jeffrey Hettinger, Justin Buchicchio, Tabbetha Dobbins, Catherine Yang. Designing Silk-silk Protein Alloy Materials for Biomedical Applications.
Journal
of Visualized Experiments, (90), e50891, doi:10.3791/50891 (2014)
61.(Book Chapter) Fang Wang, Catherine Yang, Xiao Hu. Advanced protein composite materials. In the book: Lightweight Materials from Biopolymers and Biofibers, ACS Symposium Series, 2014, in
press.
60.Samantha Mazzi, Emma Zulker, Justin Buchicchio, Breijha Anderson, Xiao
Hu. Comparative thermal analysis of Eri, Mori, Muga, and Tussar silk cocoons and fibroin fibers. J Therm Anal Calorim,
(2014). (DOI: 10.1007/s10973-013-3631-0)
59.Xiao Hu,
Waseem K. Raja, Bo An, Olena
Takarova, Peggy Cebe, David
L. Kaplan. Stability of Silk and Collagen
Protein Materials in Space. (Nature) Scientific Reports, 3, 3428, (2014). (http://www.nature.com/srep/2013/131205/srep03428/full/srep03428.html)
58.Min D. Tang-Schomer, Xiao Hu, Marie Hronik-Tupaj,
Lee W. Tien, Michael J. Whalen, Fiorenzo G. Omenetto, David L. Kaplan. Film-Based Implants for Supporting Neuron-Electrode Integrated
Interfaces for The Brain. Advanced Functional Materials, in
press (2014). (DOI: 10.1002/adfm.201303196)
57.(Book Chapter) Amy Tsui, Xiao Hu, David L. Kaplan, Curtis W. Frank.
Biodegradable Films and Foam of
Poly(3-Hydroxybutyrate-co-3-hydroxyvalerate) Blended with Silk Fibroin. Green Polymer Chemistry: Biocatalysis and Materials II, Chapter 18, pp 251-279, ACS
Symposium Series, Vol. 1144 (ISBN13: 9780841228955, eISBN:
9780841228962). (http://pubs.acs.org/doi/abs/10.1021/bk-2013-1144.ch018)
56.Eleanor M. Pritchard, Valery Normand, Xiao Hu, Stephanie Budijono,
Daniel Benczedi, Fiorenzo Omenetto, David L. Kaplan. Encapsulation of oil in silk fibroin biomaterials. Journal
of Applied Polymer Science, in press (2014). (DOI: 10.1002/app.39990)
55.Eun Seok Gil, Sang-Hyug Park, Xiao Hu, Peggy Cebe and David L. Kaplan. Impact of Sterilization on the Enzymatic Degradation and Mechanical Properties of Silk Biomaterials. Macromolecular Bioscience, in press (2014). (DOI: 10.1002/mabi.201300321)
54.Xiao Hu, Min D. Tang-Schomer, Wenwen Huang, Xiao-Xia Xia, Anthony S. Weiss, David L. Kaplan. Charge-Tunable Autoclaved Silk-Tropoelastin Protein Alloys That Control Neuron Cell Responses. Advanced Functional Materials, 23, 3875-3884, (2013).
53.Peggy Cebe, Xiao Hu, David Kaplan, Evgeny Zhuravlev, Andreas Wurm, Daniella Arbeiter, Christoph Schick. Beating the Heat - Fast Scanning Melts Beta Sheet Crystals. (Nature) Scientific Reports, 3, 1130, (2013).
52.Eleanor M Pritchard, Xiao Hu, Violet Finley, Catherine K Kuo, David L Kaplan. Effect of Silk Protein Processing on Drug Delivery from Silk Films. Macromolecular Bioscience 13, 311-320, (2013).
51.Danyu Yao, Sen Dong, Qiang Lu, Xiao Hu, David L Kaplan, Bingbo Zhang, Hesun Zhu. Salt-Leached Silk Scaffolds with Tunable Mechanical Properties. Biomacromolecules, 13(11), 3723-3729, (2012).
50.Guokui Qin, Patrick B. Dennis, Yuji Zhang, Xiao Hu, Jason E. Bressner, Zhongyuan Sun, Wendy J. Crookes-Goodson, Rajesh R. Naik, Fiorenzo G. Omenetto, David L. Kaplan. Recombinant Reflectin-Based Optical Materials. Journal of Polymer Science: Part B: Polymer Physics 51, 254-264, (2013).
2012:
49.Review: Xiao Hu, Peggy Cebe, Anthony S. Weiss, Fiorenzo Omenetto, David L. Kaplan. Protein-Based Composite Materials. Materials Today, 15(5), 208-215, (2012).
48.Guokui Qin*/ Xiao Hu*, Peggy Cebe, David Kaplan. Mechanism of resilin elasticity. Nature Communications, (2012). (*Equal contribution)
47.Jeney Zhang*, Eleanor Pritchard*, Xiao Hu, Thomas Valentin, Bruce Panilaitis, Fiorenzo G. Omenetto, David L. Kaplan. Stabilization of vaccines and antibiotics in silk and eliminating the cold chain. PNAS (Proceedings of the National Academy of Sciences of the United States of America), 109(30), 11981-11986, (2012). (*Equal contribution)
46.Rangam Rajkhowa, Xiao Hu, Takuya Tsuzuki, David L. Kaplan, Xungai Wang. Structure and Biodegradation Mechanism of Milled Bombyx mori Silk Particles. Biomacromolecules, 13(8), 2503-2512, (2012).
45.Cencen Zhang, Dawei Song, Qiang Lu, Xiao Hu, David L. Kaplan, Hesun Zhu. Flexibility Regeneration of Silk Fibroin in Vitro. Biomacromolecules, 13(7), 2148-2153, (2012).
44.F. Philipp Seib, Manfred F. Maitz, Xiao Hu, Carsten Werner, David L. Kaplan Impact of processing parameters on the haemocompatibility of Bombyx mori silk films. Biomaterials, 33, 1017-1023, (2012). (IF=7.882)
43.Shuo Sun, Ming Wang, Sarah Knupp, Yadira Soto-Feliciano, Xiao Hu, David Kaplan, Robert Langer, Daniel Anderson, Qiaobing Xu. Combinatorial Library of Lipidoids for In Vitro DNA Delivery. Bioconjugate Chemistry, 23(1), 135-140, (2012).
42.A.L. Oliveira, L. Sun, H.J. Kim, Xiao Hu, W. Rice, J. Kluge, R. L. Reis and D. L. Kaplan Aligned Silk-Based 3D Architectures for Contact Guidance in Tissue Engineering. Acta Biomaterialia, 8(4), 1530-1542, (2012). (IF=4.822)
2011:
41.Xiao Hu*, Sang-Hyug Park*, Eun Seok Gil, Xiao-Xia Xia, Anthony S. Weiss, David L. Kaplan. The influence of elasticity and surface roughness on myogenic and osteogenic-differentiation of cells on silk-elastin biomaterials. Biomaterials, 32(34), 8979-89, (2011). (*Equal contribution)
40.Xiao Hu, Karen Shmelev, Lin Sun, Eun-Seok Gil, Sang-Hyug Park, Peggy Cebe, David L. Kaplan. Regulation of Silk Material Structure by Temperature-Controlled Water Vapor Annealing. Biomacromolecules, 12(5), 1686-1696, (2011).
39.Book Chapter: Xiao Hu and David L. Kaplan. Comprehensive Biomaterials: Vol. 2, 2.212 Silk Biomaterials, Editors-Paul Ducheyne, Kevin E Healy, Dietmar E Hutmacher etc.- Elsevier Ltd., Pages 207-219, (2011). (Print ISBN: 9780080553023; Electronic ISBN: 9780080552941).
38.Wenwen Huang, Sreevidhya Krishnaji, Xiao Hu, David Kaplan, Peggy Cebe. Heat Capacity of Spider Silk-like Block Copolymers. Macromolecules, 2011, 44(13), 5295-5305, (2011).
37.Guokui Qin*, Amit Rivkin*, Shaul Lapidot, Xiao Hu, Shira B. Arinos, Or Dgany, Oded Shoseyov, David L. Kaplan. Recombinant Exon-Encoded Resilins for Elastomeric Biomaterials. Biomaterials, 32(35), 9231-9243, (2011). (*Equal contribution)
36.Xiao-Xia Xia, Qiaobing Xu, Xiao Hu, Guokui Qin, and David L. Kaplan. Tunable Self-Assembly of Genetically Engineered Silk-Elastin-Like Protein Polymers. Biomacromolecules, 12(11), 3844-3850, (2011).
35.Michelle Kinahan, Emmanouela Filippidi, Sarah Koster, Xiao Hu, Heather M. Evans, Thomas Pfohl, David L. Kaplan, Joyce Wong. Tunable Silk: Using Microfluidics to Fabricate Silk Fibers with Controllable Properties. Biomacromolecules, 12(5), 1504-1511, (2011).
34.Tara D. Sutherland, Jeffrey S. Church, Xiao Hu, Mickey G. Huson, David L. Kaplan, Sarah Weisman. Single honeybee silk protein mimics properties of multi-protein silk. PLoS ONE, 6(2), e16489, (2011).
33.Lindsay S. Wray, Xiao Hu, Daniel Schmidt, David L. Kaplan. Effect of Processing on Silk-Based Biomaterials: Reproducibility and Biocompatibility. Journal of Biomedical Materials Research-Part B, 99(1), 89-101, (2011).
2010:
32.Xiao Hu, Xiuli Wang, Jelena Rnjak, Anthony S. Weiss, David L. Kaplan. Biomaterials derived from silk-tropoelastin protein systems. Biomaterials, 31(32), 8121-8131, (2010).
31.Xiao Hu, Qiang Lu, Lin Sun, Peggy Cebe, Xiaoqin Wang, Xiaohui Zhang, David Kaplan. Biomaterials from Ultrasonication-Induced Silk Fibroin-Hyaluronic Acid Hydrogels. Biomacromolecules, 11, 3178-3188, (2010).
30.Andreas Lammel, Xiao Hu, Sang-Hyug Park, David L. Kaplan, Thomas Scheibel. Controlling silk fibroin particle features for drug delivery. Biomaterials, 31, 4583-4591, (2010).
29.Corinne R. Wittmer, Xiao Hu, Pierre-Chanel Gauthier, Sarah Weisman, David L. Kaplan, Tara D. Sutherland. Production, structure and in vitro degradation of electrospun honeybee silk nanofibers. Acta Biomaterialia, 7(10), 3789-3795, (2011).
28.Qiang Lu, Xiaoqin Wang, Xiao Hu, Peggy Cebe, Fiorenzo Omenetto, David L. Kaplan. Stabilization and Release of Enzymes from Silk Films. Macromolecular Bioscience, 10, 359-368, (2010).
27.Xiao Hu, Guokui Qin, Peggy Cebe, David Kaplan. Structure and Elasticity Mechanism of Full Length Resilin Proteins. Proceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference, 2 pages.
26.Guokui Qin, Shaul Lapidot, Keiji Numata, Xiao Hu, Sigal Meirovitch, Mara Dekel, Itai Podoler, Oded Shoseyov, David Kaplan. Expression, cross-linking and characterization of recombinant chitin binding resilin. Proceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference, 2 pages.
25.Xiao Hu, Guokui Qin, Peggy Cebe, David Kaplan. Dynamic Structure Study of Synthetic Resilin Biopolymers. Proceedings of the American Chemical Society, Polym. Mater. Sci. Eng., 2 pages. (2010 Fall Meeting)
2009:
24.Xiao Hu, Qiang Lu, David Kaplan, Peggy Cebe. Microphase Separation Controlled Beta Sheet Crystallization Kinetics in Fibrous Proteins. Macromolecules, 42 (6), 2079-2087, (2009).
23.Xiao Hu, David Kaplan, Peggy Cebe. Thermal Analysis of Protein-Metallic Ion Systems. J. Thermal Analysis, 96, 827-834, (2009).
22.Xiaoqin Wang, Tuna Yucel, Qiang Lu, Xiao Hu, David L. Kaplan. Silk Nanospheres and Microspheres from Silk/PVA Blend Films. Biomaterials, 31, 1025-1035, (2009).
21.Lei Yu, Xiao Hu, David Kaplan, Peggy Cebe. Dielectric Relaxation Spectroscopy of Hydrated and Dehydrated Silk Fibroin Cast from Aqueous Solution. Biomacromolecules, 11(10), 2766-2775, (2010).
20.Shenzhou Lu, Xiaoqin Wang, Qiang Lu, Xiao Hu, Neha Uppal, Fiorenzo Omenetto, David Kaplan. Stabilization of Enzymes in Silk Films. Biomacromolecules, 10(5), 1032-1042, (2009).
19.Guokui Qin, Shaul Lapidot, Keiji Numata, Xiao Hu, Sigal Meirovitch, Mara Dekel, Itai Podoler, Oded Shoseyov, David Kaplan. Expression, cross-linking and characterization of recombinant chitin binding resilin. Biomacromolecules, 10, 3227-3234, (2009). (IF=5.325)
18.Qiang Lu, Xiao Hu, Xiaoqin Wang, Jonathan Klugea, Shenzhou Lu, Peggy Cebe, David L. Kaplan. Water-Insoluble Silk Films with Silk I Structure. Acta Biomaterialia, 6, 1380-1387, (2009).
17.Qiang Lu, Xiaohui Zhang, Xiao Hu, David L Kaplan. Green Process to Prepare Silk Fibroin/Gelatin Biomaterial Scaffolds. Macromolecular Bioscience, 10, 289-298, (2009).
16.Antonella Motta, Devid Maniglio, Claudio Migliaresi, Hyeon-Joo Kim, Xianyan Wang, Xiao Hu, David Kaplan. Silk Fibroin Processing and Thrombogenic Responses. J. Biomaterials Science, Polymer Edition, 20 (13), 1875-1897, (2009).
15.Xiao Hu, Qiang Lu, David Kaplan, Peggy Cebe. Microphase separation restricted beta sheet self-assembly and crystallization kinetics in silk fibroin protein. Proceedings of the American Chemical Society Polym. Mater. Sci. Eng., 101, 1278-1279, (2009).
14.A. Wurm, D. Arbeiter, Xiao Hu, D. Kaplan, P. Cebe, and C. Schick. Crystallization and melting of fibrous silk protein by fast calorimetric methods. Proceedings of the 37th North American Thermal Analysis Society (NATAS) annual conference, Fall 2009.
2008:
13.Xiao Hu, David Kaplan, Peggy Cebe. Dynamic Protein-Water Relationships during Beta Sheet Formation. Macromolecules, 41(11), 3939-3948, (2008).
12.M. Pyda, Xiao Hu, Peggy Cebe. Heat Capacity of Silk Fibroin Based on the Vibration-Motion of Poly(amino acid)s in the Absence and in the Presence of Water. Macromolecules, 41(13), 4786-4793, (2008).
11.Huipeng Chen, Xiao Hu, and Peggy Cebe. Thermal Properties and Phase Transitions in Nylon-6 and Silk Fibroin Blends. J. Thermal Analysis, 93(1), 201-206, (2008).
10.Featured article: Xiao Hu, David Kaplan, Peggy Cebe. Thermal Analysis of Protein-Metallic Ion Systems. NATAS Notes, 40(4), 9-18, Fall 2008 (North American Thermal Analysis Society, www.natasinfo.org).
9. Featured article: M. Pyda, Xiao Hu, Peggy Cebe. Heat Capacity of Silk Fibroin Based on the Vibrational-Motion of Poly(amino acid)s. NATAS Notes, 40(4), 20-27, Fall 2008 (North American Thermal Analysis Society, www.natasinfo.org).
2007:
8. Xiao Hu, David Kaplan, Peggy Cebe. Effect of Water on Thermal Properties of Silk Fibroin. Thermochimica Acta, 461(1-2), 137-144, (2007).
7. Xiaoqin Wang, Esther Wenk, Xiao Hu, Guillermo R. Castro, Lorenz Meinel, Xianyan Wang, Chunmei Li, Hans Merkle, David Kaplan. Silk coatings on PLGA and alginate microspheres for protein delivery. Biomaterials, 28, 4161-4169, (2007).
6. Xianyan Wang, Xiao Hu, Andrea Daley, Olena Rabotyagova, Peggy Cebe, and David Kaplan. Nanolayer biomaterial coatings of silk fibroin for controlled release. Journal of Controlled Release, 121, 190-199, (2007).
5. Xiao Hu, David Kaplan, Peggy Cebe. The Role of Water Molecules in the Thermal Crystallization of Silk Fibroin Protein. Proceedings of the American Chemical Society Polym. Mater. Sci. Eng., 97, 559-560, (2007).
4. Xiao Hu, David Kaplan, Peggy Cebe. Beta Pleated Sheet Crystals in Silk Fibroin. Proceedings of the American Chemical Society Polym. Mater. Sci. Eng., 97, 178-179, (2007).
3. Xiao Hu, David Kaplan, Peggy Cebe. Thermal Crystallization of Silk Fibroin Protein. Proceedings of the 35th North American Thermal Analysis Society (NATAS) annual conference, Fall 2007.
2006:
2. Xiao Hu, David Kaplan, Peggy Cebe. Determining Beta Sheet Crystallinity in Fibrous Proteins by Thermal Analysis and Infrared Spectroscopy. Macromolecules, 39, 6161-6170 (2006). (IF=4.837) (Citation > 130)
2005:
1. Xiao Hu, Peggy Cebe. Isothermal Crystallization Kinetics Study of Regenerated Bombyx mori Silk Fibroin Film. Proceedings of the American Chemical Society Polym. Mater. Sci. Eng., 93, 652-653, (2005).